The Cubs and White Sox renew hostilities this weekend, this time at U.S. Cellular Field. On Saturday it will be Ryan Dempster matching up against Mark Buehrle. Dempster has been the hard luck pitcher on the Cubs this season as he is 4-5 with a 3.83 ERA.

MLB Betting Preview Chicago Cubs at Chicago White SoxSaturday, 4:05 pm Eastern – Fox

Buehrle is 7-2 with a 3.17 ERA for the Sox. “I wish the only Interleague games were the Cubs,” White Sox first baseman Paul Konerko said. “I think the games that lose intensity are the other Interleague games.”

Check out the current line for this game at SBG Global.

The Cubs and White Sox split their two games at Wrigley Field last week with one rainout. “I think that both teams have been making the playoffs and been in contention,” Konerko said. “One team won a World Series. I think the fans and everybody have their sights set on the end of the year, which, before the last couple of years, didn’t really exist. It was all about what happened in this series.”

In his last start against the Braves, Dempster allowed only two runs in 6 2/3 innings but took the loss. In his last outing against the White Sox he allowed three runs in six innings.

Buehrle pitched seven shutout innings in his last start against Cincinnati, allowing only five hits. Buehrle is 19-6 all-time in Interleague Play. He is 4-4 with a 4.57 ERA in 10 starts against the Cubs in his career.

Before this series began on Friday, the White Sox and Cubs had split their 68 Interleague meetings. “This series is like no other,” White Sox pitcher John Danks said. “Even some of our division games here don’t have the same feeling as the Cubs-Sox game. It’s just the way it is. There’s definitely a lot more tension surrounding that. It makes it fun.”

Here are the MLB Betting stats for Saturday’s game. The Cubs are 2-5 in their last 7 Interleague road games vs. a left-handed starter. The Cubs are 1-10 in Dempster’s last 11 road starts.

The White Sox are 10-2 in their last 12 Inter league home games. The White Sox are 10-4 in their last 14 vs. the National League Central. The White Sox are 45-20 in Buehrle’s last 65 home starts.

The Under is 4-1-1 in the Cubs last 6 road games vs. a left-handed starter. The Under is 5-0 in Dempster’s last 5 starts overall. The Under is 23-4 in the White Sox last 27 home games vs. a right-handed starter. The Under is 8-2 in Buehrle’s last 10 starts overall.